Sale!

Buy Lanoxin Tablets (Digoxin Tablets)

PubChem CID:ย  2724385

IUPAC:ย 3-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-3-[(2R,4S,5S,6R)-5-[(2S,4S,5S,6R)-5-[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-12,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one

Synonyms:ย Acid Phenylethylbarbituric, Gardenal, Hysteps, Luminal, Monosodium Salt Phenobarbital, Phenemal, Phenobarbital, Phenobarbital Sodium, Phenobarbital Monosodium Salt, Phenobarbitone, Phenylbarbital, Phenylethylbarbituric Acid, Sodium Phenobarbital,

CAS#: 20830-75-5

Molecular Mass: 780.949ย g/mol

Molecular Formula:ย  C41H64O14

Form: Tablets

Administration: Oral

Storage: Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. It is recommended that the product be stored at 20-25ยฐC (68-77ยฐF), however, brief excursions are permitted between 15-30ยฐC (59-86ยฐF).


Each tablet contains 125 or 250 mcg of Digoxin as active ingredient.

Digoxin, sold under the brand nameย Lanoxinย among others, is a medication used to treat variousย heart conditions.

75.00$345.00$

Description

Buy Digoxin 125 mcg Tablets Online

Buyย Digoxinย 250 mcg Tablets Online

Where to Buy Lanoxin Tabletsย  (Digoxin Tablets) Online?

You can order and getย Lanoxin tablets (Digoxin tablets) safely from this site. We are the only reliable and legit online vendor of Digoxin, pentobarbital (sodium) and other barbiturates. We offer genuine and best quality Digoxin tablets at reasonable costs. Fast and Discreet Worldwide shipping.

Also available on our website Nembutal Sodium Oral Solution, Nembutal Sodium Pills, Nembutal Sodium Oral Soluble Powder, Nembutal Sodium Raw Powder and other barbiturates.

What is Lanoxin (Digoxin)?

LANOXIN (digoxin) is a cardiac glycoside, a closely related group of drugs having in common specific effects on theย myocardium. These drugs are found in a number of plants. Digoxin is extracted from the leaves of Digitalis lanata.

LANOXIN is supplied as 125 mcg (0.125-mg) or 250 mcg (0.25-mg) tablets for oral administration. Each tablet contains the labeled amount of digoxin USP and the following inactive ingredients: corn and potato starches, lactose, and magnesium stearate. In addition, the dyes used in the 125 mcg (0.125 mg) tablets are D&C Yellow No. 10 and FD&C Yellow No. 6.

Indications and Dosage

Indications

Heart Failure in Adults

LANOXIN is indicated for the treatment of mild to moderate heart failure in adults. LANOXIN increases left ventricular ejection fraction and improves heart failure symptoms as evidenced by improved exercise capacity and decreased heart failure-related hospitalizations and emergency care, while having no effect on mortality. Where possible, LANOXIN should be used in combination with aย diureticย and an angiotensin-converting enzyme (ACE) inhibitor.

Heart Failure in Pediatric Patients

LANOXIN increases myocardial contractility in pediatric patients with heart failure.

Atrial Fibrillation in Adults

LANOXIN is indicated for the control of ventricular response rate in adult patients with chronic atrial fibrillation.

Dosage and Administration

Important Dosing Information

In selecting a LANOXIN dosing regimen, it is important to consider factors that affect digoxin blood levels (e.g., body weight, age, renal function, concomitant drugs) since toxic levels of digoxin are only slightly higher than therapeutic levels. Dosing can be either initiated with a loading dose followed by maintenance dosing if rapid titration is desired or initiated with maintenance dosing without a loading dose.

Consider interruption or reduction in digoxin dose prior to electrical cardioversion.

Useย digoxinย solution to obtain the appropriate dose in infants, young pediatric patients, or patients with very low body weight.

Loading Dosing Regimen in Adults and Pediatric Patients

For adults and pediatric patients if a loading dosage is to be given, administer half the total loading dose initially, then ยผ the loading dose every 4 to 8 hours twice, with careful assessment of clinical response and toxicity before each dose. The recommended loading dose is displayed in Table 1.

Table 1: Recommended LANOXIN Oral Loading Dose

 

Age

Oral Loading Dose, mcg/kg

5 to 10 years

20 -45

Adults and pediatric patients over 10 years

10-15

mcg = micrograms

 

Maintenance Dosing in Adults and Pediatric Patients Over 10 Years Old

The maintenance dose is based on the lean body weight, renal function, age, and concomitant products.

The recommended starting maintenance dosage in adults and pediatric patients over 10 years old is displayed in Table 2. Doses may be increased every 2 weeks according to clinical response, serum drug levels, and toxicity.

Table 2: Recommended Starting LANOXIN Maintenance Dosage in Adults and Pediatric Patients Over 10 Years Old

 

Age

Oral Maintenance Dose, mcg/kg/day (given once daily)

Adults and pediatric patients over 10 years

3.4 โ€“ 5.1

mcg = micrograms

 

Table 3 displays the recommended (once daily) maintenance dose of LANOXIN in pediatric patients over 10 years old and adult patients according to lean body weight and renal function. The doses are based on studies in adult patients with heart failure. Alternatively, the maintenance dose may be estimated by the following formula (peak body stores lost each day through elimination):

Total Maintenance Dose = Loading Dose (i.e., Peak Body Stores) x % Daily Loss/100
(% Daily Loss = 14 + Creatinine clearance/5)

Reduce the dose of LANOXIN in patients whose lean weight is an abnormally small fraction of their total body mass because ofย obesityย or edema.

Table 3: Recommended Maintenance Dose (in micrograms given once daily) of LANOXIN in Pediatric Patients Over 10 Years Old and Adults by Lean Body Weight and by Renal Functiona

 

Corrected Creatinine Clearanceb

Lean Body Weightd

Number of Days Before Steady State Achievedc

kg

40

50

60

70

80

90

100

lb

88

110

132

154

176

198

220

10 mL/min

62.5*

125

125

187.5

187.5

187.5

250

19

20 mL/min

125

125

125

187.5

187.5

250

250

16

30 mL/min

125

125

187.5

187.5

250

250

312.5

14

40 mL/min

125

187.5

187.5

250

250

312.5

312.5

13

50 mL/min

125

187.5

187.5

250

250

312.5

312.5

12

60 mL/min

125

187.5

250

250

312.5

312.5

375

11

70 mL/min

187.5

187.5

250

250

312.5

375

375

10

80 mL/min

187.5

187.5

250

312.5

312.5

375

437.5

9

90 mL/min

187.5

250

250

312.5

375

437.5

437.5

8

100 mL/min

187.5

250

312.5

312.5

375

437.5

500

7

aDoses are rounded to the nearest dose possible using whole and/or half LANOXIN tablets. Recommended doses approximately 30 percent lower than the calculated dose are designated with an *. Monitor digoxin levels in patients receiving these initial doses and increase dose if needed. .
bFor adults, creatinine clearance was corrected to 70-kg body weight or 1.73 mยฒ body surface area. If only serum creatinine concentrations (Scr) are available, a corrected Ccr may be estimated in men as (140 โ€“ Age)/Scr. For women, this result should be multiplied by 0.85.
For pediatric patients, the modified Schwartz equation may be used. The formula is based on height in cm and Scr in mg/dL where k is a constant. Ccr is corrected to 1.73 mยฒ body surface area. During the first year of life, the value of k is 0.33 for pre-term babies and 0.45 for term infants. The k is 0.55 for pediatric patients and adolescent girls and 0.7 for adolescent boys.
GFR (mL/min/1.73 mยฒ) = (k x Height)/Scr
cIf no loading dose administered.
dThe doses listed assume average body composition.

 

Maintenance Dosing in Pediatric Patients Less Than 10 Years Old

The starting maintenance dose for heart failure in pediatric patients less than 10 years old is based on the lean body weight, renal function, age, and concomitant products.

The recommended starting maintenance dose for pediatric patients between 5 and 10 years old with normal renal function is displayed in Table 4.

Table 4: Recommended Starting LANOXIN Maintenance Dosage in Pediatric Patients Between 5 and 10 Years Old

 

Age

Daily Oral Maintenance Dose, mcg/kg/day

Dose Regimen, mcg/kg/dose

5 to 10 years

6.4 โ€“ 12.9

3.2 โ€“ 6.4 Twice daily

 

The recommended maintenance dose (to be given twice daily) is presented in Table 5.

Table 5: Recommended Maintenance Dose (in micrograms given twice daily) of LANOXIN in Pediatric Patients < 10 Years of Ageaย Based upon Lean Body Weight and Renal Functiona,b

 

Corrected Creatinine Clearancec

Lean Body Weight

Number of Days Before Steady State Achievedd

kg

20

30

40

50

60

lb

44

66

88

110

132

10 mL/min

62.5

62.5*

125

125

19

20 mL/min

62.5

62.5

125

125

125

16

30 mL/min

62.5

62.5*

125

125

187.5

14

40 mL/min

62.5

62.5*

125

187.5

187.5

13

50 mL/min

62.5

125

125

187.5

187.5

12

60 mL/min

62.5

125

125

187.5

250

11

70 mL/min

62.5

125

187.5

187.5

250

10

80 mL/min

62.5*

125

187.5

187.5

250

9

90 mL/min

62.5*

125

187.5

250

250

8

100 mL/min

62.5*

125

187.5

250

312.5

7

aRecommended are doses to be given twice daily.
bThe doses are rounded to the nearest dose possible using whole and/or half LANOXIN tablets. Recommended doses approximately 30 percent lower than the calculated dose are designated with an *. Monitor digoxin levels in patients receiving these initial doses and increase dose if needed
cย The modified Schwartz equation may be used to estimate creatinine clearance. See footnote b under Table 2.
dย If no loading dose administered.

 

 

Monitor for signs and symptoms of digoxin toxicity and clinical response. Adjust dose based on toxicity, efficacy, and blood levels.

Serum digoxin levels < 0.5 ng/mL have been associated with diminished efficacy, while levels above 2 ng/mL have been associated with increased toxicity without increased benefit.

Interpret the serum digoxin concentration in the overall clinical context, and do not use an isolated measurement of serum digoxin concentration as the basis for increasing or decreasing the LANOXIN dose. Serum digoxin concentrations may be falsely elevated by endogenous digoxin-like substances.

If the assay is sensitive to these substances, consider obtaining a baseline digoxin level before starting LANOXIN and correct post-treatment values by the reported baseline level.

Obtain serum digoxin concentrations just before the next scheduled LANOXIN dose or at least 6 hours after the last dose. The digoxin concentration is likely to be 10% to 25% lower when sampled right before the next dose (24 hours after dosing) compared to sampling 8 hours after dosing (using once-daily dosing). However, there will be only minor differences in digoxin concentrations using twice daily dosing whether sampling is done at 8 or 12 hours after a dose.

Switching from Intravenous Digoxin to Oral Digoxin

When switching from intravenous to oral digoxin formulations, make allowances for differences in bioavailability when calculating maintenance dosages (see Table 6).

Table 6: Comparison of the Systemic Availability and Equivalent Doses of Oral and Intravenous LANOXIN

ย 

Absolute Bioavailability

Equivalent Doses (in micrograms)

LANOXIN Tablets

60 -80%

62.5

125

250

500

LANOXIN Intravenous Injection

100%

50

100

200

400

 

HOW SUPPLIED

Dosage Forms And Strengths

Tablets: 125 micrograms are yellow, round, scored tablets with โ€œY3Bโ€ imprinted on one side. Tablets: 250 micrograms are white, round, scored tablets with โ€œX3Aโ€ imprinted on one side.

Storage And Handling

LANOXIN (digoxin) Tablets, Scored 125 mcg (0.125 mg): Bottles of 100 with child-resistant cap (NDCย 0173-0242-55) and 1,000 (NDCย 0173-0242-75); unit dose pack of 100 (NDCย 01730242-56). Imprinted with LANOXIN and Y3B (yellow).

LANOXIN (digoxin) Tablets, Scored 250 mcg (0.25 mg): Bottles of 100 with child-resistant cap (NDC0173-0249-55), 1,000 (NDCย 0173-0249-75), and 5,000 (NDCย 0173-0249-80); unit dose pack of 100 (NDCย 0173-0249-5656). Imprinted with LANOXIN and X3A (white).

Store at 25ยฐC (77ยฐF); excursions permitted to 15 to 30ยฐC (59 to 86ยฐF) in a dry place and protect from light. Keep out of reach of children.

Order Onlineย Lanoxin Tablets

Order Online Digoxinย Tablets

lanoxin tablets,ย lanoxin tablets 0.25 mg,ย lanoxin tablets uses,ย lanoxin tablets for dogs,ย lanoxin tablets . 25 mg,ย lanoxin tablets in hindi,ย lanoxin pg tablets 62.5mcg,ย can lanoxin tablets be crushed,ย lanoxin tm tablets,ย lanoxin 0.125 mg tablets,ย digoxin tablets bp 0.25 mg,ย digoxin tablets bp,ย digoxin tablets bnf,ย lanoxin pg blue tablets,ย lanoxin tablet composition,ย lanoxin tablet company,ย lanoxin tablet cost,ย digoxin tablets colour,ย digoxin tablets cost,ย lanoxin tablet dosage,ย digoxin tablets dose,ย digoxin tablets dosage,ย digoxin tablets dissolution,ย lanoxin digoxin tablets,ย lanoxin tablet side effects,ย digoxin tablets for dogs,ย digoxin tablets for sale,ย lanoxin tablet used for,ย lanoxin tablets hindi,ย digoxin tablets hindi,ย digoxin heart tablets,ย digoxin tablets ip 0.25mg,ย digoxin tablets ip,ย digoxin tablets ip 0.25mg in hindi,ย digoxin tablets images,ย digoxin tablets in india,ย digoxin tablets information,ย lanoxin tablet leaflet,ย digoxin tablets lp,ย lanoxin tablet mims,ย lanoxin tablet manufacturer,ย digoxin tablets msds,ย lanoxin tablet 0.125 mg,ย lanoxin tablet price,ย lanoxin tablet picture,ย digoxin tablets patent,ย lanoxin tablet strengths,ย lanoxin tab side effect,ย digoxin tablets side effects,ย digoxin tablets spc,ย digoxin tablets strength,ย digoxin tablets substitute,ย lanoxin tablet tamil,ย digoxin tablets to liquid conversion,ย digoxin tablets to liquid,ย digoxin tablets to elixir,ย digoxin tablets toxicity,ย lanoxin tablet use in hindi,ย lanoxin tablet uses in tamil,ย lanoxin tablet uses in telugu,ย digoxin tablets uses,ย digoxin tablets usp monograph,ย lanoxin 0.25 tablet uses,ย digoxin tablets what are they for,ย www.lanoxin tablets,ย lanoxin tablet 0.25,ย digoxin tablets 0.25mg,ย digoxin 0.125mg tablets (yellow),ย digoxin 0.125mg tablets,ย digoxin tablets 125 micrograms,ย digoxin tablets 125 mcg,ย digoxin 125 microgram tablets,ย digoxin 125 mcg tablets,ย digoxin 125mg tablets,ย digoxin tablets 250 micrograms,ย digoxin tablets 250 mcg,ย digoxin 250 mcg tablets,ย lanoxin .25 tablet,ย digoxin tablets 250,ย lanoxin tablet 500mg,ย digoxin tablets 62.5 mg,ย digoxin tablets 62.5 mcg,ย buy lanoxin tablets, buy lanoxin tablets online, where to buy lanoxin tablets, lanoxin dosage, lanoxin side effects, lanoxin tablets dosage, lanoxin tablets side effects, lanoxin administration, buy digoxin online, buy digoxin tablets online, where to buy digoxin tablets, digoxin dosage, digoxin side effects, digoxin tablets dosage, digoxin tablets side effects, digoxin administration, digoxin buy online , digoxin for animals,ย Boehringer Digoxina, Digacin, Digitek, Digoregen, Digoxin, Digoxina Boehringer, Digoxine Nativelle, Dilanacin, Hemigoxine Nativelle, Lanacordin, Lanicor, Lanoxicaps, Lanoxin, Lanoxin PG, Lanoxin-PG, Lenoxin, Mapluxin, Nativelle Digoxine, Nativelle Hemigoxine,

Reviews

There are no reviews yet.

Be the first to review “Buy Lanoxin Tablets (Digoxin Tablets)”

Your email address will not be published. Required fields are marked *