Description
Buy Phenobarbital 60 mg Tablets Online
Where to Buy Phenobarbital Tablets Online?
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What is Phenobarbital ?
Phenobarbital is a barbiturate, nonselective central nervous system depressant which is primarily used as a sedative hypnotic and also as an anticonvulsant in subhypnotic doses.
Phenobarbital, also known asย phenobarbitoneย orย phenobarb, is a medication recommended by theย World Health Organizationย for the treatment of certain types ofย epilepsyย inย developing countries. In the developed world it is commonly used to treat seizures inย young children,ย while other medications are generally used in older children and adults.ย Phenobarbital is occasionally used to treatย trouble sleeping,ย anxiety, andย drug withdrawalย and to help with surgery.
Indications and Dosage
Indications
a. Sedatives.
b. Hypnotics, for the short-term treatment ofย insomnia, since they appear to lose their effectiveness forย sleepย induction and sleep maintenance after 2 weeks.
c. Preanesthetics.
d. Long-term anticonvulsants for the treatment of generalized tonic-clonic andย corticalย local seizures. And, in the emergency control of certainย acuteย convulsive episodes, e.g., those associated withย status epilepticus,ย cholera,ย eclampsia,ย meningitis,ย tetanus, and toxic reactions to strychnine or local anesthetics.
Dosage and Administration
Suggested doses ofย phenobarbitalย for specific indications are as follows:
a.ย Pediatricย Oral Dosage (as recommended by theย American Academy of Pediatrics):
Preoperative: 1 to 3 mg/kg.
b. Adult Oral Dosage:
1. Daytimeย sedative: 30 to 120 mg daily in 2 to 3 divided doses.
2. Bedtime hypnotic: 100 to 320 mg.
3.ย Anticonvulsant: 50 to 100 mg 2 to 3 times daily.
Dosages of phenobarbital must be individualized with full knowledge of their particular characteristics and recommended rate of administration. Factors of consideration are the patient’s age, weight, andย condition.ย Parenteralย routes should be used only when oral administration is impossible or impractical.
Anticonvulsant use:ย Aย therapeuticย anticonvulsant level of phenobarbital inย serumย is 10 to 25 ยตg/mL. To achieve theย bloodย levels considered therapeutic in children, higher per-kilogram dosages are generally necessary for phenobarbital and most other anticonvulsants. In children and infants, phenobarbital at loading dose of 15 to 20 mg/kg produces blood levels of about 20 ยตg/mL shortly after administration.
In status epilepticus, it is imperative to achieve therapeutic blood levels of phenobarbital as rapidly as possible. Because a barbiturate-inducedย depressionย may occur along with a postictal depression once the seizures are controlled, it is important, therefore, to use the minimal amount required, and to wait for the anticonvulsant effect to develop before administering a second dose.
Phenobarbital has been used in the treatment andย prophylaxisย ofย febrileย seizures. However, it has not been established that prevention of febrile seizures influences the subsequent development ofย epilepsy.
Special patient population:ย Dosage should be reduced in the elderly or debilitated because these patients may be more sensitive to phenobarbital. Dosage should be reduced for patients with impairedย renalย function orย hepaticย disease.
HOW SUPPLIED
Oral Tablets
15 mg – Each white round tablet imprinted ร 026 contains 15 mg of Phenobarbital. Tablets are supplied in bottles of 1000 (NDC 0228-2026-96).
30 mg – Each white, round, scored tablet imprinted ร 028 contains 30 mg of Phenobarbital. Tablets are supplied in bottles of 1000 (NDC 0228-2028-96).
60 mg – Each white, round, tablet imprintedย EP902ย contains 60 mg of Phenobarbital. Tablets are supplied in bottles of 1000
100 mg – Each white, round, scored tablet imprinted ร 030 contains 100 mg of Phenobarbital. Tablets are supplied in bottles of 1000 (NDC 0228-2030-96).
Dispense in well-closed containers as defined in the USP. Store at controlled room temperature 15ยบ- 30ยบ C (59ยบ- 86ยบ F).
SIDE EFFECTS
The following adverse reactions and theirย incidenceย were compiled from surveillance of thousands of hospitalized patients.
More than 1 in 100 patients:The most commonย adverse reactionย estimated to occur at a rate of 1 to 3 patients per 100 is:
- Nervous system:ย Somnolence.
Less than 1 in 100 patients:Adverse reactions estimated to occur at a rate of less than 1 in 100 patients listed below, grouped byย organย system, and by decreasing order of occurrence are:
- Nervous system:ย Agitation, confusion, hyperkinesia,ย ataxia,ย CNSย depression, nightmares, nervousness,ย psychiatricย disturbance, hallucinations,ย insomnia,ย anxiety, dizziness, thinking abnormality.
- Respiratory system:ย Hypoventilation,ย apnea.
- Cardiovascular system:ย Bradycardia,ย hypotension,ย syncope.
- Digestive system:ย Nausea, vomiting, constipation.
- Other reported reactions:ย Headache, injection site reactions, hypersensitivity reactions (angioedemaย skinย rashes, exfoliativeย dermatitis),ย fever,ย liverย damage, megaloblasticย anemia followingย chronicย phenobarbital use.
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